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TUhjnbcbe - 2021/8/23 23:53:00
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INTRODUCTION

Thecerebralcortex,orneocortex,iscriticaltokeymammalianskillssuchaslanguage,sociability,andsensorimotorcontrol.Thisstructureconsistsofdozensofspecializedtypesofneuronsorganizedacrosslayersandareas,whicharegeneratedduringdevelopmentbydiversetypesofprogenitors.Newbornneuronsthenundergosequentialmolecularprogramsthatdrivetheirspecificlocalandlong-rangecircuitconnectivityandadultfunction.Althoughtheyarenecessaryforpropercorticalfunctiontoemerge,thesemyriadsofmolecularandcellulardevelopmentalprocessesprovidemultiplepointsofvulnerabilityfor“corticalmalformations,”whichcausevarious

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