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Science从皮层发育畸形的机制研究中 [复制链接]

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北京看白癜风那家比较好 http://baidianfeng.39.net/a_cjzz/130905/4251012.html

INTRODUCTION

Thecerebralcortex,orneocortex,iscriticaltokeymammalianskillssuchaslanguage,sociability,andsensorimotorcontrol.Thisstructureconsistsofdozensofspecializedtypesofneuronsorganizedacrosslayersandareas,whicharegeneratedduringdevelopmentbydiversetypesofprogenitors.Newbornneuronsthenundergosequentialmolecularprogramsthatdrivetheirspecificlocalandlong-rangecircuitconnectivityandadultfunction.Althoughtheyarenecessaryforpropercorticalfunctiontoemerge,thesemyriadsofmolecularandcellulardevelopmentalprocessesprovidemultiplepointsofvulnerabilityfor“corticalmalformations,”whichcausevarious

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